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WSVA8-0185
FELINE MEDICINE
BIOCHEMICAL AND ELECTROCARDIOGRAPHIC PROFILE IN CATS WITH OBSTRUCTIVE FELINE LOWER URINARY TRACT DISEASE
A. Melchert1, M. Araujo Martins Fernandes1,
M.L. Gomes Lourenço1, A. Sarita Cruz Aleixo1,
P.T. Chalfun Guimarães Okamoto1, S. algueiro Geraldes1, J. Cavalcante1, R. Kiomi Takahira1
1School of Veterinary Medicine and Animal Science -
Univ Estadual Paulista - UNESP, Veterinary Clinical Departamet, Botucatu, Brazil
INTRODUCTION
Urethral obstruction is a common condition in domestic male cats. Many problems can occur due to the interruption of the urinary flow, such as acid-base and electrolytic changes that results in abnormalities in the myocardial cells potential action and, therefore, in electrocardiogram.
OBJECTIVES
The aim of this study was to characterize the electrocardiographic, biochemical and hematological changes of cats with urethral obstruction.
METHODS
Eighteen male cats with first urethral obstruction were evaluated in the clinical routine of Veterinary Medicine and Animal Science School – UNESP, Botucatu, SP.
RESULTS
The most significant electrolytic change was hyperkalemia, in 76.5% of the animals. 17.7% was hypokalemic and 5.9% with normal potassium levels (5.4±1.7). The cats were azotemic, with serum urea (267.8±181.9) and creatinine (7.9±6.0) above reference range in 94.7% and 79% of the cats, respectively. It was observed as well hypoalbuminemia in 57.9 % of cats (2.5±0.3). There was a marked leukocytosis in 79% of
the cats (32147±16782) characterized by neutrophilia (29700±16444). In electrocardiogram 81.3% showed sinus rhythm, however 6.25% presented sinus bradycardia
and 12.5% sinus tachycardia. Other relevant findings
were widened QRS complex (87.5% of the animals) and prolonged P-wave duration (62.3%) and Q-T interval (50%). There were also abnormalities such as ventricular extrasystole (6.3%), atrial still, right bundle branch block and fascicular block (12.5%). The cats which presented serum potassium levels above 7.0 (22.2%) had as the most important irregularities fascicular block and atrial still.
CONCLUSIONS
It is important to monitor the cardiac rhythm in cats with urethral obstruction, since electrocardiographic changes are relatively frequent.
Your Singapore, the Tropical Garden City
WSVA8-0163
FELINE MEDICINE
PHYLOGENETIC CHARACTERIZATION OF FELINE RETROVIRUSES IN HUNGARY
A. Szilasi1, L. Dénes1, G. Balka1, K. Heenemann2
1University of Veterinary Medicine, Pathology, Budapest, Hungary
2Veterinärmedizinische Universität Leipzig, Institut für Virologie, Leipzig, Germany
INTRODUCTION
Feline retroviral infections are common in domestic cats causing AIDS-like diseases like Feline Immunodeficiency Virus (FIV), or neoplastic diseases like Feline Leukemia Virus (FeLV).
OBJECTIVES
Our aim was to characterize these retroviral infections among domestic cats, examine the prevalence in Hungary, and to make a phylogenetic analysis from the discovered strains.
METHODS
Prevalence data were counted after examination of EDTA-anticoagulated whole blood samples of client- owned cats in Hungary. We carried out ELISA snap tests and polymerase chain reaction (PCR) on each specimen. Sequence analysis was done only on PCR-positive strains. In case of both viruses, amplification of pol and env sequences was performed. Individual sequence
text files in FASTA-format were created after alignement of both unidirectional electropherograms. Multiple sequence alignement were performed with ClustalW software, accepting the default parameters. Phylogenetic trees were created with BioEdit software with maximum likelihood-based phylogenetic analysis.
RESULTS
In this survey we collected more than 300 blood specimens and phylogenetic analyses were carried out on those contained FIV and/or FeLV. Data of pol and env sequences showed, that Hungary has mostly subtype
A strains of FIV, which correlates to data provided by surrounding countries.
CONCLUSIONS
This study filled a gap of European feline retroviral surveys, providing information of Hungarian distribution of FIV and FeLV strains among domestic cats. The data correlates with phylogenetics of surrounding countries, showing mainly subtype A FIV infections.
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