Page 681 - WSAVA2018
P. 681

WSVA8-0038
GASTROENTEROLOGY
PREVALENCE OF CANINE HEPATIC LESIONS FROM PERCUTANEOUS ULTRASOUND-GUIDE TRU-CUT LIVER BIOPSY IN THAILAND
S. Assawarachan1
1Faculty of Veterinary Medicine- Kasetsart University, Department of Companion Animal Clinical Sciences, Bangkok, Thailand
INTRODUCTION
The definitive diagnosis of canine hepatobiliary diseases required histopathology. To date, percutaneous ultrasound-guided tru-cut biopsy remains the most common technique to obtain the samples.
OBJECTIVES
The objective of the present study was to survey the prevalence of hepatic lesions of dogs in Thailand.
METHODS
A survey of hepatic lesion in dogs with chronic elevated liver enzyme was conducted in 76 dogs (median age [range]: 10.8 years [1.7 – 16.5 years]; 42 (55.3%) females and 34 (44.7%) males) in Thailand during January
2016- January 2018 using ultrasound-guided Tru-cut liver biopsy. The liver samples were processed for histopathology analysis. The associations between anemia (PCV<35) or thrombocytopenia (platelet< 200,000/cumm) with liver lesions were also evaluated.
RESULTS
Of these 76 dogs, there were 46 (60.5%) small, 21 (27.6%) medium and 9 (11.8%) large breed dogs. The histological diagnosis revealed 41 (53.9%) with hepatitis, 9 (11.8%), 25 (32.9%) with fibrosis, 21 (27.6%) with vacuolar hepatopathy and 8 (10.5%) with steroid hepatopathy. There were 14 (18.4%) dogs with anemia, 14 (18.4%) dogs with thrombocytopenia and 3 (3.9%) dogs with both anemia and thrombocytopenia. Dogs with liver tumors were associated with the presence of anemia (p=0.009). Older dogs (age >8 years) were associated with the presence of thrombocytopenia (p=0.003). There was only one (1.3%) dog with bleeding complication after the liver biopsy.
CONCLUSIONS
In conclusion, percutaneous ultrasound-guided Tru-
cut liver biopsy is a safe and non-invasive method to diagnose canine hepatobiliary diseases. Caution should be taken in dogs with anemia and thrombocytopenia due to a possible bleeding complication after the biopsy.
Your Singapore, the Tropical Garden City
WSVA8-0016
GASTROENTEROLOGY
A SYSTEMIC CANINE PROTOTHECOSIS IN CENTRAL REGION OF THAILAND
T. Jumnansilp1, T. Ongvisespaibool1, P. Songprayoon2
1Kasetsart University Veterinary teaching hospital, critical care unit and Gastrointestinal and endocrine clinic, Bangkok, Thailand
2Kasetsart University Veterinary teaching hospital, Out-patient Department and neurologic department, Bangkok, Thailand
INTRODUCTION
Protothecosis is a disease caused by achlorophyllic algae. The most common clinical presentation is protracted hemorrhagic enteritis. Colon is the most commonly affected portion but the organisms can affect many organs.
OBJECTIVES
To demonstrate an effectiveness treatment protocol for canine protothecosis
METHODS
A 4-years old, neutered female, Thai Bangkaew
dog was referred to Kasetsart University Veterinary Teaching Hospital (KUVTH) with the history of 7 months hematochezia and azotemia. The dog did not response
to the previous treatment with long-termed antibiotics. Colonoscopy demonstrated the generalized inflammation and focal hemorrhage from colon to rectum. The cytology showed granulomatous inflammation with possible Prototheca organisms. The treatment protocols were symptomatic treatment and Itraconazole 5 mg/kg orally once daily. However, the dog developed acute blindness, retinal detachment with pyogranulomatous retinitis and neurological signs with disoriented after 3 months of the treatment. Repeated cytology from rectal scraping revealed a large number of Prototheca spp. The treatment regimen then was changed to amphotericin B intravenously 1 mg/kg 2-3 times a week together with fluconazole 5mg/kg orally twice daily. Subcutaneous fluid was also provided and renal profile was monitored regularly.
RESULTS
After 4 months of this treatment protocol, the clinical signs were improved and the number of Prototheca spp. derived from rectal scraping dramatically decreased.
CONCLUSIONS
Systemic Protothecosis can affect many organs and results in death. However, with early diagnosis and appropriate management, the dog may has favorable outcome and increase survival time. Rectal scraping is a valuable tool for early diagnosis of Protothecosis as it is non-invasive technique and inexpensive.
            679
            





























































   679   680   681   682   683