Page 722 - WSAVA2018
P. 722

 25-28 September, 2018 | Singapore
WSVA8-0137
ONE HEALTH
SERODETECTION AND RISK ANALYSIS OF LEPTOSPIRAL INFECTION IN DOGS AND DOG HANDLERS (SHELTERED AND WORKING)
S.H. Goh1, S.F. Lau1, R. Ismail2, P.A. Megat Abdul Rani3, T.B. Mohd Mohidin4, A.R. Bahaman5, S.K. Bejo6, R. Radzi1, K.H. Khor1
1University Putra Malaysia, Faculty of Veterinary Medicine- Department of Veterinary Clinical Studies, Serdang- Selangor, Malaysia
2The National University of Malaysia, Faculty of Medicine- Department of Community Health, Bangi- Selangor, Malaysia
3University Putra Malaysia, Faculty of Veterinary Medicine- Department of Companion Animal Medicine & Surgery, Serdang- Selangor, Malaysia
4University of Malaya, Faculty of Science- Institute of Biological Science- Division of Microbiology, Kuala Lumpur, Malaysia
5University Putra Malaysia, Department of Veterinary Pathology & Microbiology, Serdang- Selangor, Malaysia
6University Putra Malaysia, Faculty of Veterinary Medicine- Department of Veterinary Pathology & Microbiology, Serdang- Selangor, Malaysia
INTRODUCTION
A global upward trend of leptospirosis warrants unified initiative in managing this zoonotic disease. Dogs were speculated to contribute in disease transmission posing risk to humans.
OBJECTIVES
Study aimed to detect leptospiral infection serologically and examined the risk factors towards leptospirosis among dogs and dog handlers.
METHODS
Serum were collected from 266 apparently healthy vaccinated (quadrivalent vaccine) dogs and 194 dog handlers. Microscopic agglutination test (MAT) was performed using 20 leptospiral serovars with a cut-off titre ≥1:100 (dog) and ≥1:50 (dog handlers). Risk factors were analysed using odd ratios.
RESULTS
Seventy dogs (26.3%) were seropositive mainly against serovars icterohaemorrhagiae, ballum, bataviae and javanica (titres:1:100-1:800). Sixty-seven dog handlers (34.5%) were seropositive mainly against serovars grippotyphosa, icterohaemorrhagiae and malaysia (titres:1:50-1:200). Risk factors for dogs and dog handlers were as shown in Table 1.
Risk Factor
Table1: Risk factors of leptospiral infection among dogs and dog handlers
CONCLUSIONS
Seropositive dogs were likely due to post-vaccination, post-exposure or subclinical infection, hence further investigation were required. Vaccine immunity may not be adequate as other serovars were detected. Low titres among dog handlers could indicate post-exposure. Rat contact poses risk for both groups. Prolonged contact time with dogs increased risk for handlers. Therefore, leptospirosis awareness among dog handlers could assist disease prevention
 Odd Ratio p
Confidence Interval
 Dog
Rat Contact
 4.29
  0.05
 0.98-18.78
Sharing Area
 5.87
  0.01
 2.25-15.32
Environment Setting
 1.8
  0.03
 1.06-3.21
Dog Handlers
Rat Contact
 6.60
  0.01
 2.80-15.60
Small Mammal Contact
 4.46
  0.01
 1.91-10.44
Contact Time with Dog
 4.20
  0.01
 1.70-10.50
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43RD WORLD SMALL ANIMAL VETERINARY ASSOCIATION CONGRESS AND 9TH FASAVA CONGRESS














































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